A SYSTEMATIC REVIEW OF THE LEVEL OF EVIDENCE IN ECONOMIC EVALUATIONS OF MEDICAL DEVICES: THE EXAMPLE OF VERTEBROPLASTY AND KYPHOPLASTY.

A Systematic Review of the Level of Evidence in Economic Evaluations of Medical Devices: The Example of Vertebroplasty and Kyphoplasty.

ContextEconomic evaluations are far less frequently reported for medical devices than for drugs.In addition, little is known about the quality of existing economic evaluations, particularly for innovative devices, such as those used in vertebroplasty and kyphoplasty.ObjectiveTo assess the level of evidence provided by the available economic evaluat

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Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses of Cryptococcus neoformans

ABSTRACT The basidiomycetous fungus Cryptococcus neoformans has been known to be highly radiation resistant and has been found in fatal radioactive environments such as the damaged nuclear reactor at Chernobyl.To elucidate the mechanisms underlying the radiation resistance phenotype of C.neoformans, we identified genes affected by gamma radiation t

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Noncoding Vault RNA1-1 Impairs Intestinal Epithelial Renewal and Barrier Function by Interacting With CUG-binding Protein 1Summary

Background & Aims: Small noncoding vault RNAs (vtRNAs) are involved in many cell processes important for health and disease, but their pathobiological functions in the intestinal epithelium are underexplored.Here, we investigated the role of human vtRNA1-1 in regulating intestinal epithelial renewal and barrier function.Methods: Studies were co

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